Yes, toothpaste has been known to help reduce the redness and size of a pimple due to its drying properties. However, it is important to use caution as toothpaste is not formulated for skin application and may cause irritation or allergic reactions in some individuals. If you decide to try using toothpaste on a pimple, it’s best to choose a plain white toothpaste and apply a small amount to the affected area, leaving it on for a short period before rinsing off. It is recommended to do a patch test on a small area of skin to check for any adverse reactions before applying it to a larger area. If you have sensitive skin or experience any discomfort after applying toothpaste, it is best to discontinue use and consult a dermatologist for proper acne treatment.