Blackhead holes, also known as enlarged pores, can fill back up if proper skin care measures are not taken. It is a common occurrence for pores to become clogged again, leading to the reappearance of blackheads. To prevent this, it is essential to maintain a consistent skincare routine involving cleansing, exfoliating, and using products that help manage sebum production. Regular exfoliation, using products with salicylic acid or retinol, and keeping the skin clean can help prevent pores from getting clogged and reduce the likelihood of blackheads reoccurring. If you have concerns about your skin, it is advisable to consult with a dermatologist for personalized advice and treatment options.